| Vertical Transmission of Hepatitis C Virus in Infant of the Mother Who Had Active Hepatitis C during Pregnancy |
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Mi-Jeong Lee1, Mi-Jeong Lee2 |
1Department of Pediatrics, Korea Cancer Center Hospital, Seoul, Korea
2Department of Clinical Pathology, Korea Cancer Center Hospital, Seoul, Korea |
| 활동성 C형 간염 산모로부터 출생한 영야에서 C형 간염Virus의 수직전파 1례 |
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이미정1, 이동순2 |
1원자력병원 소아과
2원자력병원 임상병리과 |
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| Abstract |
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Vertical transmission of hepatitis C virus(HCV) has been reported recently. The authors experienced one case of vertical transmission of HCV in infant of the mother who had active hepatitis C durig pregnancy. At delivery, HCV RNA(+), IgG anti HCV Ab(+), IgM anti HCV Ab(+), mile elevation of liver aminotransferase level and mile fatty liver of ultrasonography were found in the mother. At birth HCV RNA(+) and IgG anti HCV Ab(+) were found in the baby. HCV RNA(+), IgG anti HCV Ab(+) and IgM anti HCV Ab(+) were noted on the day 107 in the serum of the infant. We used reverse transcriptase polymerase chain reaction(RT-PCR) technique to find very small amount of HCV RNA in the serum. All those findings suggest vertical transmission of HCV from mother to infant. |
| Key Words:
Hepatitis C virus, Vertical transmission, Reverse transcriptase polymerase chain reaction |
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