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Outbreak of Non-typhoidal Salmonellosis in neonates

Journal of the Korean Pediatric Society 1995;38(1):20-26.
Published online January 15, 1995.
Outbreak of Non-typhoidal Salmonellosis in neonates
N.M. Park, M.J. Chey, M.J. Jeong, H.S. Kim, K.H. Kim, H.S. Lee
Department of Pediatrics, Chungang Gil Hospital, Incheon, Korea
신생아에서 발생한 유행성 비장티푸스성 살모넬라증에 대한 임상적 관찰
박난미, 최명재, 정미진, 김희섭, 김길현, 이학수
중앙 길병원 소아과
During the period from Jun. 24, 1991 to Aug. 31, 1991, we experienced 6 cases of non-typhoidal salmonella and 18 cases with symptoms suggesting salmonellosis. The results obtained were as follows; 1) Mean age on admission was 9¡¾6 days and mean body weight was 3.3¡¾0.3kg. All cases were fullterm neonate. 2) 12 pts were transferred from nursery becasuse of diarrhea (50.0%), 7 pts were readmitted after discharge from nursery (29.2%), and 1 pt was case of onser during admission in nICU(4.2%) 4) Nature of diarrhea was loose(29.2%), watery(45.8%), or mucoid(25.0%), and mean duration of diarrhea was 11¡¾6 days 5) Culture yielded non-typhoidal salmonella in 4 cases(16.6%) in blood, 3 cases(12.5%) in urine, 1 cases(4.2%) in stool, and 1 case(4.2%) in joint fluid. 6) On ABGA, metabolic acidosis developed in 83.4% and mean pH was 7.22¡¾0.13 7) Susceptability to antibiotics showed sensitivity to amikacin (77.8%), gentamicin(55.6%), clindamycin(55.6%), shereas resistancy to ampicillin(77.8%), chloramphenicol(66.7%), and kanamycin(66.7%) 8) There was no expired case, and septic arthritis in the left shoulder joint developed in 1 case(4.2%) as a complication 9) All possible endeavours to search for the infection sources failed to discover the index cases on this occasion.
Key Words: Neonates, Non-typhoidal salmonellosis

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