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Clninical Features of Rotaviral Gastroenteritis in Neonates

Korean Journal of Pediatrics 2005;48(10):1121-1125.
Published online October 15, 2005.
Clninical Features of Rotaviral Gastroenteritis in Neonates
Shin-I Park, Hae Oak Kwon, Jun Ho Lee, Su Jin Jung
Department of Pediatrics, College of Medicine, Pochon CHA University, Sungnam, Korea
신생아에서 로타바이러스 위장관염의 임상양상에 대한 고찰
박신이, 권혜옥, 이준호, 정수진
포천중문의과대학교 소아과학교실
Correspondence: 
Su Jin Jung, Email: jinped@hanmail.net
Abstract
Purpose
: Rotavirus is the main cause of infantile diarrheal disease worldwide, especially in patients 3-24 months of age. Infants younger than 3 months of age are relatively protected by transplacental antibody. So the purpose of this study is to evaluate the clinical features and severity of neonatal rotaviral gastroenteritis less than 1 month of age.
Methods
: A retrospective chart review was established of 62 neonates less than 1 month of age and with a diagnosis of rotaviral gastroenteritis who had been admitted to Pochon CHA University between June 2002 through July 2004. The rotavirus was examined by stool latex agglutination.
Results
: During 2 years, the total number of admitted patients for rotaviral gastroenteritis was 688 and among these, less than 1 month of age accounted for 9%(62). The occurrence was generally even distribution from January to July(7.14?.0) but since then decreased(2.4?.8). The most common chief complaint was mild fever(46%) when admitted which subsided within 1 hospital day in most patients. 4 patients had seizure and cyanosis with no typical symptoms of rotaviral gastroenteritis. During admission, all the patients had diarrhea. 17% of the patients had leukocytosis and positive C-reactive protein. In one patient, stool occult blood test was positive but there was no necrotizing gastroenteritis evidence. The mean period of hospital day was 5.8?.5 and breast-milk feeding was 62.9%.
Conclusion
: Neonatal rotaviral gastroenteritis is not a rare disease. Most patients have fever and diarrhea and improve through conservative therapy but a few patients may have severe complications so we must be more cautious about the hygiene for prevention.
Key Words: Rotavirus , Neonates


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