Clinical and Experimental Pediatrics

Original Article

Neurology

Efficacy and tolerability of adjunctive perampanel treatment in children under 12 years of age with refractory epilepsy

Yuni Yun, Dongsub Kim, Yun-Jeong Lee, Soonhak Kwon, Su-Kyeong Hwang

Clin Exp Pediatr. 2019;62(7):269-273. Published online December 26, 2018

Purpose: There is limited data on the use of perampanel in children under 12 years of age. We evaluated the efficacy and tolerability of adjunctive perampanel treatment in children under 12 years of age with refractory epilepsy. Methods: This retrospective observational study was performed in Kyungpook National University Hospital from July 2016 to March 2018. A responder was defined as a...

DOI: https://doi.org/10.3345/kjp.2018.06863

Intravenous levetiracetam versus phenobarbital in children with status epilepticus or acute repetitive seizures

Yun-Jeong Lee, Mi-Sun Yum, Eun-Hee Kim, Tae-Sung Ko

Clin Exp Pediatr. 2016;59(1):35-39. Published online January 22, 2016

Crossref 8

Purpose

This study compared the efficacy and tolerability of intravenous (i.v.) phenobarbital (PHB) and i.v. levetiracetam (LEV) in children with status epilepticus (SE) or acute repetitive seizure (ARS).

Methods

The medical records of children (age range, 1 month to 15 years) treated with i.v. PHB or LEV for SE or ARS at our single tertiary center were retrospectively reviewed. Seizure termination was defined...

DOI: https://doi.org/10.3345/kjp.2016.59.1.35

Outcome after relapse in childhood and adolescent osteosarcoma : single institution experience in Korea

Yun-Jeong Lee, Hyun-Jae Lee, Dong-Ho Kim, Jung-Sub Lim, Jun-Ha Lee, Kyung-Duk Park, Dae-Geun Jeon, Soo-Yong Lee

Clin Exp Pediatr. 2008;51(1):78-83. Published online January 15, 2008

Purpose : Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. Although survival rate of osteosarcoma patients has markedly improved, about 20-30% of patients still have a relapse. This study was aimed to find factors that influence postrelapse survival of osteosarcoma in childhood and adolescents. Methods : Between 1985 and 2004, of 461 patients who were diagnosed...

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