Clinical and Experimental Pediatrics

Case Report

Successful sulfonylurea treatment in a patient with permanent neonatal diabetes mellitus with a novel KCNJ11 mutation

Sung Yeon Ahn, Gu-Hwan Kim, Han-Wook Yoo

Clin Exp Pediatr. 2015;58(8):309-312. Published online August 21, 2015

Permanent neonatal diabetes mellitus refers to diabetes that occurs before the age of 6 months and persists through life. It is a rare disorder affecting one in 0.2-0.5 million live births. Mutations in the gene KCNJ11, encoding the subunit Kir6.2, and ABCC8, encoding SUR1 of the ATP-sensitive potassium (K_ATP) channel, are the most common causes of permanent neonatal diabetes mellitus....

DOI: https://doi.org/10.3345/kjp.2015.58.8.309

Original Article

Excess of leptin inhibits hypothalamic KiSS-1 expression in pubertal mice

Sung Yeon Ahn, Sei Won Yang, Hee Jae Lee, Jong Seon Byun, Ji Yeon Om, Choong Ho Shin

Clin Exp Pediatr. 2012;55(9):337-343. Published online September 14, 2012

Crossref 8

Purpose

Leptin has been considered a link between metabolic state and reproductive activity. Defective reproductive function can occur in leptin-deficient and leptin-excessive conditions. The aim of this study was to examine the effects of centrally injected leptin on the hypothalamic KiSS-1 system in relation to gonadotropin-releasing hormone (GnRH) action in the initial stage of puberty.

Methods

Leptin (1 µg) was injected directly into...

DOI: https://doi.org/10.3345/kjp.2012.55.9.337

Factors Affecting the Increments of Body Mass Index in Adult Survivors of Childhood Brain Tumors

Jae Ho Yoo, Sung Yeon Ahn, Choong Ho Shin, Sei Won Yang

Clin Exp Pediatr. 2004;47(9):970-977. Published online September 15, 2004

Purpose : The purpose of this study was to evaluate the factors affecting the increments of body mass index(BMI) in adult survivors from childhood brain tumors. Methods : We retrospectively reviewed medical records of 63 patients who were diagnosed with brain tumors and treated at Seoul National University Children's Hospital between 1982 and 2000. We evaluated the factors affecting adult BMI(aBMI)...

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The Effects of Gonadotropin-Releasing Hormone Agonists on Final Height and its Related Factors in Patients with True Precocious Puberty

Sung Yeon Ahn, Jae Ho Yoo, Choong Ho Shin, Sei Won Yang

Clin Exp Pediatr. 2004;47(6):647-655. Published online June 15, 2004

Purpose : The aim of this study was to evaluate the effects of treatment with GnRH agonists on final height(FH) and the influencing factors on height gains. Methods : Twenty-five girls and five boys with true precocious puberty, who were treated with GnRH agonists for more than one year and had attained final height, were evaluated retrospectively. We analysed auxological parameters...

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Cited By 22	Retinopathy of prematurity: a review of epidemiology and current treatment strategies
Cited By 20	Genetic factors in precocious puberty
Cited By 18	Global relationship between parent and child obesity: a systematic review and meta-analysis
Cited By 14	Gross motor dysfunction and balance impairments in children and adolescents with Down syndrome: a systematic review
Cited By 13	Etiological and pathophysiological enigmas of severe coronavirus disease 2019, multisystem inflammatory syndrome in children, and Kawasaki disease

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