Clinical and Experimental Pediatrics

Original Article

Neurology

Evaluation of hematologic profile may be needed for patients treated with oxcarbazepine

Gu Hyun Jung, Su Jeong You

Clin Exp Pediatr. 2019;62(8):312-316. Published online April 11, 2019

Purpose: The major side effects of treatment with oxcarbazepine (OXC) are skin rash and hyponatremia. Hematologic side effects are reported rarely. The aim of this study was to investigate the rate and types of the hematologic side effects of OXC. Methods: The medical records of 184 patients diagnosed with epilepsy or movement disorder and on OXC monotherapy, at the Department of...

DOI: https://doi.org/10.3345/kjp.2019.00017

The age and dose-related hyponatremia during carbamazepine and oxcarbazepine therapy in epileptic children

Kyu Ha Lee, Jun Hyuk Song, Sung Ho Cha, Sa Jun Chung

Clin Exp Pediatr. 2008;51(4):409-414. Published online April 15, 2008

Purpose : To assess the prevalence of hyponatremia in epileptic children receiving carbamazepine or oxcarbazpine, we investigate serum sodium changes according to age, serum carbamazepine level, and daily oxcarbazepine dosage, and the prevalence of symptoms of hyponatremia. Methods : We reviewed the clinical data of the 197 children receiving carbamazepine and/or oxcarbazepine with or without antiepileptic therapy. And these were classified...

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Efficacy and safety of oxcarbazepine in epileptic children

Hye Kyung Shin, Yoon Lee, Jee-Yeon Lee, Wooksun Choi, So-Hee Eun, Baik-Lin Eun, Young Sook Hong, Joo Won Lee

Clin Exp Pediatr. 2008;51(2):162-169. Published online February 15, 2008

Purpose : Oxcabarzepine (OXC), newly recommended antiepileptic drug, has been prescribed for patients with partial seizures and generalized tonic clonic seizures in Korea from 1999. There are limited reports about an efficacy of OXC therapy in epileptic children in Korea. This study evaluated the efficacy and safety of OXC in the light of our experience. Methods : The patients, who had...

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