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Original Article
Clinical outcome of acute myocarditis in children according to treatment modalities
Hyun Jung Kim, Gyeong-Hee Yoo, Hong Ryang Kil
Clin Exp Pediatr. 2010;53(7):745-752.   Published online July 31, 2010
Purpose

There is currently little evidence to support intravenous immune globulin (IVIG) therapy for pediatric myocarditis. The purpose of our retrospective study was to assess the effects of IVIG therapy in patients with presumed myocarditis on survival and recovery of ventricular function and to determine the factors associated with its poor outcome.

Methods

We reviewed all consecutive cases of patients with myocarditis with...

Clinical characteristics and progress of Kawasaki disease patients who had early treatment with intravenous immune globulin
So-Yoon Park, Young Hwan Lee
Clin Exp Pediatr. 2007;50(10):1005-1010.   Published online October 15, 2007
Purpose : To determine the optimal time of high dose intravenous immune globulin (IVIG) treatment, we analysed the clinical characteristics and progress of a group of Kawasaki disease patients who had early treatment with IVIG. Method : A retrospective study was conducted of 188 patients with Kawasaki disease who were admitted to Yeungnam University Medical Center from January 2000 to December...
Echocardiographic Evaluation of Left Ventricular Function in Kawasaki Disease : Effect of Immune Globulin
Mi-Jin Jung
Clin Exp Pediatr. 2004;47(6):665-671.   Published online June 15, 2004
Purpose : The purpose of this investigation was to identify the impaired myocardial function and improvement with immune globulin in Kawasaki disease. Methods : The myocardial performance and diastolic function were evaluated in 52 patients. M-mode and Doppler echocardiography were performed before(pre) and after immune globulin treatment : two to nine days(pre), five to 15 days(period one), 14 to 35...
Manifestation of Coronary Artery Lesions after Immunoglobulin Re-treatment in Initial Immunoglobulin-resistant Kawasaki Disease
Hyo Jung Suk, In Sung Kim, Jo Won Jung
Clin Exp Pediatr. 2004;47(4):424-429.   Published online April 15, 2004
Purpose : To evaluate the predictable factors for why initial intravenous immune globulin(IVIG) therapy failed and the outcome of coronary lesions after additional IVIG retreated in initial IVIG- resistant Kawasaki disease(KD). Methods : Retrospective studies were performed on 284 cases of KD treated with one episode of high-dose IVIG and 63 cases with additional IVIG retreatment at this hospital from January...
High-dose Intravenous Immune Globulin Retreatment in Kawasaki Disease
So Yun Shim, Mi Young Heo, Hae Soon Kim, Sejung Sonh
Clin Exp Pediatr. 2002;45(10):1273-1277.   Published online October 15, 2002
Purpose : To determine clinical features, laboratory findings and cardiac abnormalities of highdose immune globulin(IVIG) retreatment in patients with Kawasaki disease, and to report effectiveness of retreatment. Methods : Retrospective study of 174 children diagnosed with Kawasaki disease at Ewha Mokdong hospital from March, 1999 to July, 2001. Results : Twenty(11.5%) of 174 patients were retreated with high-dose IVIG. After this, only two patients(1.1%) did not...
Treatment of Intravenous Immune-Globulin Resistant Kawasaki Disease with Corticosteroids
Dae-Eui Hong, Kyung-Yil Lee, Ji-Whan Han, Sung-Soo Hwang, Kyong-Su Lee
Clin Exp Pediatr. 1997;40(10):1453-1457.   Published online October 15, 1997
Purpose : To evaluate the efficacy of steroid therapy on prevention of development and progression of coronary artery aneurysm in intravenous immune globulin(IVIG)-resistant Kawasaki disease, we treated three children with high dose of intravenous methylprednisolone followed by low dose oral prednisolone. Methods : We selected three children with Kawasaki disease who did not repond or who initially responded but soon developed recrudescent fever after retreatment...
High-Dose Intravenous Immune Globulin Therapy for Hyperbilirubinemia Caused by ABO Incompatibility
Dong Sung Kim, Dong Un Kim, Ji Whan Han, Sung Soo Whang, Kyung Yil Lee, Man Kyu Yang
Clin Exp Pediatr. 1993;36(8):1073-1079.   Published online August 15, 1993
Four newborn infants with hyperbilirubinemia, caused by ABO blood group incompatibility, were treated with high-dose intravenous immune globulin (IVIG). As soon as the diagnosis was clinically suspected, these infants received conventional treatment including phototherapy and were monitored closely for bilirubin levels. When bilirubin concentrations reached the risk point in spite of pjototherapy, IVIG was given at a dose of 1g/kg for...
Effect of immune globulin on the prevention of coronary artery aneurysm in Kawasaki disease.
Mi Jin Jung, Chung Il Noh, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1991;34(5):668-676.   Published online May 31, 1991
We compared the efficacy of each modality of treatment group in reducing the frequency of coronary artery aneurysm in children with Kawasaki syndrome. Group 1 (26 cases)-aspirin alone: Group 2 (26 cases)-intravenous gamma globulin, 400 mg per kilogram of body weight per day for five consecutive days, plus aspirin; Group 3 (21 cases)-intravenous gamma globulin, single dose of 2.0 g per kilogram of body...
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