Clinical and Experimental Pediatrics

Review Article

Infection

Consideration in treatment decisions for refractory Mycoplasma pneumoniae pneumonia

Hye-Kyung Cho

Clin Exp Pediatr. 2021;64(9):459-467. Published online February 10, 2021

• To avoid unnecessary exposure to secondary antibiotics, it is needed to diagnose Mycoplasma pneumoniae (MP) pneumonia carefully, especially when unresponsiveness to macrolide is suspected.
• Serologic and molecular tests for MP infection and excluding respiratory infection caused by other pathogens might be considered.
• It is necessary to continuously monitor antibiotic susceptibility of MP, and efforts to lower antibiotic pressure are required.

DOI: https://doi.org/10.3345/cep.2020.01305

Pulmonology

Benefits and risks of therapeutic alternatives for macrolide resistant Mycoplasma pneumoniae pneumonia in children

Hyeon-Jong Yang

Clin Exp Pediatr. 2019;62(6):199-205. Published online March 15, 2019

Crossref 11

Although Mycoplasma pneumoniae pneumonia (MPP) has been generally susceptible to macrolides, the emergence of macrolide-resistant MPP (MRMP) has made its treatment challenging. MRMP rapidly spread after the 2000s, especially in East Asia. MRMP is more common in children and adolescents than in adults, which is likely related to the frequent use of macrolides for treating M. pneumoniae infections in children....

DOI: https://doi.org/10.3345/kjp.2018.07367

Systemic use of fluoroquinolone in children

Soo-Han Choi, Eun Young Kim, Yae-Jean Kim

Clin Exp Pediatr. 2013;56(5):196-201. Published online May 28, 2013

Crossref 40

Fluoroquinolones are an important class of antibiotics that are widely used in adult patients because of their broad spectrum of activity, good tissue penetration, and oral bioavailability. However, fluoroquinolone use in children is limited because juvenile animals developed arthropathy in previous experiments on fluoroquinolone use. Indications for fluoroquinolone use in patients younger than 18 years, as stated by the U.S....

DOI: https://doi.org/10.3345/kjp.2013.56.5.196

The use of fluoroquinolone in children

Jae Kyun Hur

Clin Exp Pediatr. 2008;51(10):1042-1046. Published online October 15, 2008

The fluoroquinolones are an important group of antibiotics widely used in the treatment of various infectious diseases in adults, as a result of an excellent spectrum of activity, good tissue penetration and convenient ways of administration. In recent decades, there has been extensive development, clinical investigation, licensure and use of fluoroquinolone antibiotics. However, the use of fluoroquinolones in children has...

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