Meningeal Leukemia in Children: A Review of 11 Cases |
Sang Woo Kim, Min Ja Pai, Ae Ra Shin, Yung Kil Chang, Chang Yee Hong |
Department of P ediatrics, Seoul National University Hospital |
小兒의 白血病腦體症狀(Meningeal Leukemia) 의 臨皮的觀察 |
金相祐, 裵敏子, 申愛羅, 張永吉, 洪影義 |
서 울大學校 醫科大學小兒科學敎室 |
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Abstract |
Clinical observation was made on 11 cases of meningeal leukemia out of 146 cases leukemia during
10 years from 1962 to 1971 at department of pediatrics, Seoul National University Hospital.
1. Sex ratio of male: female was 9:2. Considering the sex ratio the total leukemic children in Korea
(male: female=3 : 1), the predominance in male is not significant. 2. The peak age was 5 to 9 years.
3. The incidence according to the types of lenkemia: 6 cases in acute lymohccytic leukemia and 3 cases
in acute myelocytic. 4. The time interval between the diagnosis and lenkemia to the onset of meningeal lenkemia was average 8 months and 22 days. 5. Common chief complaints were headache (10 cases) and nausea and vomiting (8 cases), papilledema and neck-stiffness or Kernig’s sign were positive in half of the cases.
6. The characteristic CSF findings of meningeal lenkemia was pleccytcsis. The CSF glucose level and
the protein level was variable.
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