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Leukemia in Childhood with Mediastinal Masses

Journal of the Korean Pediatric Society 1972;15(4):319-325.
Published online April 30, 1972.
Leukemia in Childhood with Mediastinal Masses
Min Ja Pai, Soon Young Kim, Don Hee Ahn, Chang Yee Hong
Department of Pediatrics, College of Medicine, Seoul National University
縱隔洞腫痛를 同伴한 小兒白血病
裵敏子, 金舜英, 安敦姬, 洪影義
서울犬學校 醫科大學 小兒科學敎室
Abstract
Six cases o£ acute leukemia with mediastinal masses are reported with a review of relevant literature.. Out of 105 patients wi h leukemia who had been admitted to the Department of Pediatrics, Seoul. National University Hospital for the last 6 years, six cases had huge mediastinal masses on the chest x-ray examination. In 3 of them the masses were located in the anterior mediastinum, suggesting enlargement of the thymus. On admission these cases had more or less severe dyspnea and facial edema,, and 2 of them were initally suspected as heart failure and osteomyelitis respectively. All of the 6. cases were acute lymphocytic leukemia and treated with combinations of prednisolone, 6-mercaptcpurine^ methotrexate and vincristine, showing remarkable improvement of clinical features in a few days.


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