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Electrocardiographic Abnormalities, and the Serum Transaminase and Lactic Dehydrogenase Activity in Diphtheric Myocarditis

Journal of the Korean Pediatric Society 1972;15(3):197-205.
Published online March 31, 1972.
Electrocardiographic Abnormalities, and the Serum Transaminase and Lactic Dehydrogenase Activity in Diphtheric Myocarditis
Goo Young Chung, Chui Hong Paek, Sang Ha Suh, Dong Sup Han
Department of Pediatrics, Kyungfiook National University, School of Medicine, Taegu, Korea
디프테리아心筋炎에 있어서 心電圖 異常과 血淸 transaminase 및 lactic dehydrogenase activity 에대하여
鄭九容, 白哲弘, 徐相夏, 韓東變
慶北大學校醫科大學小兒科學敎室
Abstract
The serum transaminase and lactic dehydrogenase activity were studied in 28 children with diphtheria who were admitted to the Kyungpook University Hospital during the one year and 4 month pericd frem April 1970 to July 1971, and their relation to electrocardiographic abnormalities was observed. The results were as follows: 1) Fifteen (54%) of 82 cases complicated diphtheric myocarditis, clinically and electrccardiographically. 2) In general, the levels of SGOT and SGPT were elevated in the children with myocarditis, and the former tended to be increased more markedly. However, the levels of SGPT were elevated markedly in association with extensive hepatic congestion. 3) The elevation of both SGOT and SGPT levels correlated well with the degree of clinical severity and electrocardiographic abnormalities, though the variation among individuals was observed. 4) The high levels of LDH encountered in children with severe myocarditis, especially with extensive liepatic congestion.


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