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H-I Antibody Titers of Japanese B Encephalitis in the Blood of Mothers and Newborn Infants

Journal of the Korean Pediatric Society 1973;16(11):839-843.
Published online November 30, 1973.
H-I Antibody Titers of Japanese B Encephalitis in the Blood of Mothers and Newborn Infants
Moon Jae Park, Goo Young Chung, Gui Ran Lee, Dong Sup Han
Department of Pediatrics, Kyungpook National University School of Medicine Taegu, Korea
夏季腦炎에 對한 産母 및 新生兒 血中 抗體價에 對하여
朴文在, 鄭九容, 李貴蘭, 韓東燮
慶北學校醫科大學小兒科學敎室
Abstract
Hemagglutination-inhibiting antibody (H-I antibody) titers of Japanese B encephalitis were measured by the method of Clarke and Casals, with sera of 12 healthy mothers and 17 normal newborn infants who were admitted to Kyungpook University Hospital during period from May through November of 1971. In order to remove the IgM, sera were treated with 2-mercaptorethanol (2-ME). Among sera obtained in pre-epidemic season (May to June), four o£ 7 newborns (57.1%) and 2 c-f 5 mothers (40%) had undetectable levels (<1 : 10). Mean antibody titer of newborns having detectable levels was 1 : 33 (range 1 : 10 to 1 : 80) and that of mothers having detectable levels was 1 : 20. Among sera obtained during-and in post-epidemic season (Sept, to Nov.) 4 of 10 newborns (40%) and 4 of 7 mothers (57.1%) had undetectable levels. Mean antibody titer of newborns having detectable levels was 1 : 56 (range 1: 10 to 1: 80)


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