| A Study of Serum CRP During the First Week of Life |
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Jong Ju Kim |
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Dept, of Pediatrics, College of Medicine, Busan National University |
| 신생아에 있어서의 혈청 CRP 반응 |
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김종주 |
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부산대학교 의과대학 소아과학교실 |
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| Abstract |
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Determinations of serum C-reactive protein were performed on peripheral blood specimens of 34 non-infected and 22 infected infants during the first week of life. The average frequency of positive CRP was 38.8% in non-infected fullterm and 44.6% in non-infected premature infants, but the difference of positive rate was not significant. The peak incidence of positive CRP was noted on 4 th day in fullterm and on the 2 nd postnatal day in non-infected premature infants. The difference in positive rate of serum CRP was significant between infected and non infected groups, but not significant between fullterm and premature groups. The intensity of the positive reactions in the majority of the non-infected groups was not greater than 1 mm, whereas 2 mm or more in those newborns with infections. Among the infected groups, the more severe the infection, the greater the intensity of the positive reactions. It is suggested that CRP is not transferred across the placental barrier. In conclusion, serum CRP determination, serum CRP determination can be a valuable diagnostic aid in infections during the first week of life when the usual laboratory methods are not helpful. |
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