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Clin Exp Pediatr > Accepted Articles
DOI: https://doi.org/10.3345/kjp.2019.00675    [Accepted]
Published online November 12, 2019.
Drug Allergy in Children: What Should We Know?
Ji Soo Park, Dong In Suh 
Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea
Correspondence: 
Dong In Suh, Tel: +82-2-2072-3625, Fax: +82-2-743-3455, Email: dongins0@snu.ac.kr
Received: 15 June 2019   • Revised: 8 November 2019   • Accepted: 12 November 2019
Abstract
Drug allergy ‘label’ may have consequences of a lifetime for a child. Many children with alleged drug allergy are proven to be tolerant to the culprit medication when challenged. The field of drug hypersensitivity (DH) is a recently evolving field of research, with still a lack of studies in children regarding the epidemiology and diagnostic tools. Clinical history is significant to diagnose and classify the type of DH in children. Diagnostic tools are evaluated in a limited number of children, so the guidelines are mainly in line with adult guidelines. In this paper, we aim to review the clinical characteristics, main drugs, risk factors, and diagnosis of DH to aid in the accurate diagnosis in children.
Key Words: Adverse drug reaction, Drug allergy, Drug hypersensitivity, Drug provocation test




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