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Leukocyte Alkaline Phoshatase Activity in Japanese Encephalitis.

Journal of the Korean Pediatric Society 1979;22(12):1019-1026.
Published online December 15, 1979.
Leukocyte Alkaline Phoshatase Activity in Japanese Encephalitis.
Chan Yung Kim, Jung Hee Lee
Department of Pediatrics, College of Medicine, Busan National University, Korea.
일본뇌염 환아의 백혈구 Alkaline phosphatase활성
김찬영, 이정희
부산대학교 의과대학 소아과학교실
The leukocyte alkaline phosphatase(LPA) activity in vaious stage of Jap. Encephalitis, which was admitted to Busan National University hospital from July to September in 1978, was investigated histochemically with the Tomonaga's naphthol AX-MX phosphate fast blue RR method. The author measured and compared with circulating leukocyte. Neutrophil and LAP activities. Patients were investigated the difference of sex and age, and compared to LAP activity and the prognosis of Jap. Encephalitis. The results were summerized as follows. 1. The Scores of LAP activity in acute of Jap. Encephalitis(3.22) were significantly higher than that of mid stage(2.48), recovery stage(2.37) and the control group(2.24). 2. The LAP activity was not influenced by sex and age. 3. The increas of DAP activity was found in the patients with leukocytosis charaterized by neutrophilia and it was relatively parallel with the increase of circulating neutrophil count. 4. In comparison to LAP activity and the prognosis in Jap. Encephalitis, ingeneral, LAP activity was relatively increases as the prognosis was become poor, but it was insignificant, statistically.

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