Journal of the Korean Pediatric Society 1980;23(10):798-808.
Published online October 15, 1980.
Clinical Studies on the Patent Ductus Arteriosus.
Baek Keun Lim1, Sung Kyu Lee1, Duk Jin Yon1, Seung Nok Hong2
1Department of Pediatirics and Chest Surgery College of Medicine, Yonsei University, Korea.
2Department of Chest Surgery College of Medicine, Yonsei University
동맥관개존증 환자의 임상적 관찰
任百根1, 李升圭1, 尹德鎭1, 洪承祿2
1연세대학교 의과대학 소아과학교실
2연세대학교 의과대학 흉곽외과학교실
Patent Ductus Arteriosus is one of the most common congenital heart diseases. The symptoms and clinical findings in patients with typical patnet ductus arteriosus are well recognized. That not all patient with ductus arteriosus have the typical clinical findings is well documented. Since the poor prognosis of untreated patent ductus arteriosus and good results of surgical intervention are fairly well established fact, it is important that all altered in according to hemodynamic changes depending on the pulmonary pressure, amount of shunt, degree of resistance of pulmonary circulation. This series comprises 165 patients of patent ductus arteriosus who had been admitted to Severance Hospital from Apr. 1964 to Aug. 1979. An attempt was made to correlate the hemodynamic data with age. The results of this study may be summarized briefly as follows : 1.Of the 165 patients, 67 were male and 98 were female. Their age range from 1 day to 48 years. About 50% of all patients was below 10 years. 2.Major symptoms on admission were frequent URI, exertional dyspnea, palpitation and evaluation of known congenital heart disease etc. 3.Of 165 patients, continuous murmur was audible in 128 patients and systolic murmur in 28 patients. 4.The children (below 15 years of age) had the variable distribution of pulmonary to systemic flow ratio (Qp/Qs) Most of adult had the Qp/Qs of below 3. 5.Severe pulmonary hypertension was noted in 13% of right heart catheterized patients. 6.There was no obvious correlation between aging and pulmonary wascular resistance or pulmonary hypertension. 7.There was linear correlation between the diameter of ductus and pulmonary blood flow. 8.The left atrium to aortic root dimension ratio in echocardiogram showed correlation with the pulmonary to systemic flow ratio measured at catherization (r=0.45) 9.Operative mortality was 2.5% in 165 cases of isolated patent ductus arteriosus.

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