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A Case of Diabetes Insipidus associated with Suprasellar Germinoma.

Journal of the Korean Pediatric Society 1980;23(12):1048-1053.
Published online December 15, 1980.
A Case of Diabetes Insipidus associated with Suprasellar Germinoma.
Soo Ok Lee1, Hye Yung Hwang1, Woo Hyun1, Sang Jhoo Lee1, Dong Wha Lee2
1Department of Pediatrics, Soon Chun Hyang College, Korea.
2Department of pathology, Soon Chun Hyang College, School of Medicine, Seoul, Korea.
Suprasellar germinoma 를 同伴한 尿崩症 1 例
李水玉1, 黃惠映1, 玄 堣1, 李尙柱1, 李東華2
1順天鄕 醫科大學 小兒科學敎室
2順天鄕 醫科大學 臨床病理學 敎室
We report I case of diabetes insipidus associated with suprasellar germinoma, obstructive hydrocephalus and both optic nerve atrophy. In this patient, symptoms of increased intracranial pressure was preceded by characteristic polyuria and polydipsia. The water restriction and pitressin test resulted in central originated diabetes insipidus. Computerized tomography in the brain revealed smooth marginated rounded mass density measuring 3.9 cm obliterating 3rd ventricle and extending to suprasellar region. On neurosurgical operation, egg sized tumor mass was noted in suprasellar area with complete obstruction of 3rd ventricle. The cytological and histopathological findings revealed malignant atypical teratoma(Ectopic pinealoma) which is extremely rare in pediatric age. The patient was received partial excision of tumor mass and ventriculo-peritoneal shunt. After operation, the patient was exhibited progressive renal failure and discharged against doctors order without improvement. We also briefly reviewed with related literatures.

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