Journal of the Korean Pediatric Society 1981;24(3):221-228.
Published online March 15, 1981.
The Nitroblue Tetrazoliom Dye Reduction Test in Epidemic Encephalitis Children.
Young Youn Choi, Kong In KWon, Hyung Suk Byun, Kyung Ryong Huh, Chull Sohn
Department of Pediatrics, Chonnam University Medical School
流行性腦炎 患兒에서의 Nitroblue Tetrazolium 檢査
崔榮倫, 權公仁, 邊洞錫, 許敬龍, 孫 澈
全南大學校 醫科大學 小兒科學敎室
Abstract
Nitroblue Tetrazolium (NBT) dye can be reduced to water insoluble formazan by peripheral neutrophils during phagocytosis. A study was performed to evaluate the clinical significance of the NBT dye test in epidemic encephalitis children. The results obtained from the NBT dye test in 100 patients with epidemic encephalitis and 14 healthy children were asfollows; 1.The percentage and the absolute number of NBT positive neutrophils and total neutrophil count were significantly increased in epidemic enc-ephalitis. 2.The more the total neutrophil count, the higher the percentage and the absolute number of the NBT positive neutrophils (p 0.001). 3.There was positive correlation between the percentage of NBT positive neutrophils and total white blood cell count, total neutrophil count or body temperature recorded at the time of the NBT test(p0.001), but no correlation was found between the percentage of NBT positive neutrophils and mental state of the patients at the time of NBT test (p 0.1). 4.Ther was no correlation between the peripheral blood neutrophil count and the cerebrospinal fluid neutrophil count (p 0.1).
Key Words: NBT, Neutropil Count, Epidemic Enceaphalitis




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