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A Case of Disseminated Cryptococcosis with Skin Lesion and Miliary Shadows of the Lung.

Journal of the Korean Pediatric Society 1982;25(4):399-403.
Published online April 30, 1982.
A Case of Disseminated Cryptococcosis with Skin Lesion and Miliary Shadows of the Lung.
Chan Ho Bang1, Sang Keun Chi1, In Ho Kim1, Sang Woo Kim1, Ill Hyang Ko2
1Department of Pediatrics, Paik Hospital in Seoul, In-je Medical College, Korea.
2Department of Clinical Pathology, Paik Hospital in Seoul, In-je Medical College, Korea.
속립성 폐음영을 보인 전신파종성 Cryptococcosis 1 례
方燥活1, 池雜根1, 金仁鎬1, 金相社1, 高一香2
1인제의대부속 서울백병원 소아과
2인제의대부속 서울백병원 임상병리과
Abstract
A Case of disseminated cryptococcosis in a 5-year old girl is reported. Although twenty four pediatric cases of cryptococcosis were reported in Korea for the past 15years, this case's clinical picture is interesting and make diagnostic difficulties from miliary tuberculosis. She was transferred from a local clinic under the impression of miliary tuberculosis with chest X-ray showing miliary shadows. Mantoux test showed strong positive. She was not vaccinated BCG and had a history of contact with tuberculous patient for a month. Cough, fever and abdominal pain were persisted in spite of antituberculous medications(INH & RMP). CSF examination revealed cryptococcus cyst. Facial skin lesions which looked like Moluscum contagiosum at first became to be umbilicated and disseminated. It was diagtococcal lesions with little inflammatory response. In spite of treatment with 5-FC and Amphotericin B, her general condition became worse and died of respiratory failure. A brief review of the literature was done.
Key Words: Cryptococcosis, dissminated, Millary tuberculosis


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