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Superoxide Dismutase Activity in Down Syndrom.

Journal of the Korean Pediatric Society 1986;29(4):361-374.
Published online April 30, 1986.
Superoxide Dismutase Activity in Down Syndrom.
Moon Sook Lee1, Hae Woon Chang1, Kun Soo Lee1, Ja Hoon Koo1, Kun Young Sohn2
1Department of Pediatrics, School of Medicine, Kyung-Pook National University, Taegu、Korea
2Department of Biochemistry, School of Medicine, Kyung-Pook National University, Taegu、Korea
다운증후군 환아에 있어서 가용형 Superoxide dismutase (SODs) 활성치
이문숙1, 장해운1, 이건수1, 구자훈1, 손건영2
1경북대학교 의과대학 소아과학교실
2경북대학교 의과대학 생화학교실
Abstract
Superoxide dismutase activity of erythrocyte in 20 cases of 21-trisomy Down syndrome between 2 months and 15 years old age and 13 cases of age-matched normal children were checked at Department of Pediatrics and Department of Biochemistry, School of Medicine, Kyung-Pook National University. The results were following: Mean superoxide dismutase activity in normal children was 202.25 U/gmHb and in Down syndrome 291.69 U/gmHb, and the ratio of normal to Down syndrome was 1 : 1.44. There were no statistically significant differences in superoxide dismutase activity acco- rding to age and sex in normal and Down syndrome.
Key Words: Superoxide dismutase, Down syndrome.


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