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A Clinical Study on Intraventricular Hemorrhage in Premature Neonate.

Journal of the Korean Pediatric Society 1986;29(9):933-939.
Published online September 30, 1986.
A Clinical Study on Intraventricular Hemorrhage in Premature Neonate.
Youg Suk Koh
Department of Pediatrics, College of Medicine, Ewha Womans University
미숙아 뇌실내출혈에 관한 연구
고영숙
이화여자대학교 의과대학 소아과학교실
Abstract
Intraventricular hemorrhage is one of the most important neurologic lesion of the premature neonates. Total 23 cases of intraventricular hemorrhage were studied prospectively from March, 1984 to August, 1985 and their medical records were analyzed. The results were as follows: 1) The incidence of intraventricular hemorrhage was 13.8% and that of premature neonate born weighing less than 1.50kg and at less than 28 weeks gestatiom was 42.2%. 2) The onset of intraventricular hemorrhage was within the first two days of life in 78.2%. 3) The grades of intraventricular hemorrhage were grade I in 8 cases, grade I in 7 cases, grade H in 2 cases and grade ]V in 6 cases. 4) The mortality of intraventricular hemorrhage was 34.8%, and was 0% for grade I, 28.6% for grade E, 100% for grade Iff and 66.7% for grades . On follow up of 8 cases among 15 surviving infants, hemorrhage was resorbed and hydrocephalus didn’t developed on computed tomography and neurologic findings were normal except 1 case with mild hypotonia. 5) The clinical findings of intraventricular hemorrhage were change of activity or muscle tone, abnormal respiration, decrease of hematocrit more than 10%, hypotension, seizure, and temperature instability in frequency. 6) The risk factors associated with intraventricular hemorrhage were gestational age less than 32 weeks, birth weight less than 1.50kg, asphyxia, resuscitation, hyaline membrane disease apnea, disseminated intravascular coagulopathy, coagulation abnormality, hypoxia, liypercarbia, acidosis, continuous postive airway pressure and ventilator. 7) At autopsy, the locations of intracranial hemorrhage were consistent with those by computed tomography.
Key Words: Intraventricular hemorrhage in premature neonate.


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