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A Study on Hormonal Change of Lh, FSH, and Testosterone and Testicular Volumes in Pubertal Mal Children.

Journal of the Korean Pediatric Society 1986;29(9):979-987.
Published online September 30, 1986.
A Study on Hormonal Change of Lh, FSH, and Testosterone and Testicular Volumes in Pubertal Mal Children.
Heung Dong Kim1, Duk Hi Kim1, Ki Keun Oh2
1Department of Pediatrics,Yonsei University, College of Medicine,Seoul, Korea
2Department of Radiology, Yonsei University, College of Medicine,Seoul, Korea
사춘기 연령 남아의 호르몬과 고환 , 용적의 변화에 관한 연구
김흥동1, 김덕희1, 오기근2
1연세대학교 의과대학 소아과학교실
2연세대학교 의과대학 방사선과학교실
Abstract
The mechanism involved in pubertal changes has not been clearly demonstrated, but evidence has been accumulated that hormonal changes are responsible for this pubertal changes. We studied the height, weight, testicular volume, bone age, LH, FSH, and testosterone, "by Tanner stage of pubic hair development in 134 pubertal male children with no previous endocrine disease, who admitted at Yonsei University Medical Center, from June 1984 to July 1985. The results were as follows: 1) Height, weight, and bone age were increased with puberty progressed. 2) Bone age was closely correlated with chronological age(p<0.0001). 3) Testicular volumes were enlarged with the progression of pubertal stage and chronological age, although no difference was found between right and left testicular volumes. 4) The mean serum levels of LH were elevated gradually with the progression of Tanner stage. The mean value of LH at Tanner stage was significantly higher than that at Tanner stage I. But no significant diffrences in LH levels were found after Tanner stage K. 5) Mean serum level of FSH at Tanner stage I was significantly increased as compared with that at Tanner stage I, while there were no significant differences among Tanner stage H, I, ]y and V. 6) Concentrations of serum testosterone were elevated with Tanner stage advanced, showing significant increase at each Tanner stage although no significant increase was observed at Tanner stage V. 7) There were significant correlations of serum testosterone and bone age as well as testicular volumes.
Key Words: Puberty, LH: Luteinizing hormone, FSH: Follicle stimulating hormone, Testosterone, Testicular volume.


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