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Heparin Therapy for Disseminated Intravascular Coagulation in Childhood.

Journal of the Korean Pediatric Society 1987;30(6):658-663.
Published online June 30, 1987.
Heparin Therapy for Disseminated Intravascular Coagulation in Childhood.
Byung Ryul Choi, Yong Hoon Park, Jeong Ok Hah
Department of Pediatrics, College of Medicine, Yeungnam University, Taegu, Korea
소아의 혈관내 응고 증후군에서 Heparin의 치료 효과
최병렬, 박용운, 하정옥
영남대학교 의과대학 소아과학교실
Abstract
A clinical trial for the therapeutic effect of heparin on DIC was conducted on 22 patients of DIC who were admitted to the pediatric department of Yeungnam University Hospital from September 1, 1984 to May 31, 1986. In addition to the conservative treatment, intensive care of underlying disease and specific replacement therapy for DIC, heparin was administered to the one-half of the patients alternatively in order of admission sequence and compared the progress of DIC between study group and control group. Six of 11 patients (54.5%) with heparin treatment and 7 of 11 patients (63.6%) without heparin treatment were recovered from DIC in clincal symptoms and laboratory findings. Heparin therapy in this study neither improved the recovery rate of DIC nor aggravated the bleeding tendency.
Key Words: Heparin therapy, DIC.


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