| A Clinical Studey on Reye Syndrome. |
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Myung Ho Oh, Hung Sub Choi, Chang Hwi Kim, Sang Jhoo Lee |
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Department of Pediatrics, College of Medicine, Soon Chun Hyang University, Seoul, Korea |
| Reye 증후군의 임상적 고찰 |
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오명호, 최홍섭, 김창휘, 이상주 |
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순천향의과대학 소아과학교실 |
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| Abstract |
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We took clinical study for 47 cases of Reye syndrome at S.C.H. University Hospital during last 8
years from Jan:, 1979 to Dec., 1986.
The results obtained were as follows;
1) There was no significant difference in annual incidence and the seasonal incidence was highest
in sumer and autumn.
2) The sex ratio of male to female was 1:1.4.
3) Among 47 cases, 34 cases (72.3%) were under 1 year of age.
4) Of the 47 cases, the preceeding illnesses were upper respiratory infection in 34 cases (72.2%),
gastroenteritis in 5 cases (10.6%), upper respiratory infection with gastroenteritis in 5 cases (10.6%),
pneumonia in 2 cases (4.3%), and chicken pox in 1 case (2.1%).
5) The manin clinical symptos were nausea and vomiting (80.9%), fever (74.5%), hyperventilation
(59.6%), and hepatomegaly (48.9%).
6) The mortality was high in patients with elevated serum ammonia (≧ 300 ug/dl) and prolonged
Prothrombin time ((≧ 14 sec).
7) According to Lovejoy’s classificatin, 17 cases (38.3%) were in stage III and IV on the admission.
The higher the stage, the higher the mortality.
8) The overall mortality rate was 44.7%.
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| Key Words:
Reye syndrome.
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