Journal of the Korean Pediatric Society 1987;30(11):1243-1251.
Published online November 30, 1987.
A Clinical Studey on Reye Syndrome.
Myung Ho Oh, Hung Sub Choi, Chang Hwi Kim, Sang Jhoo Lee
Department of Pediatrics, College of Medicine, Soon Chun Hyang University, Seoul, Korea
Reye 증후군의 임상적 고찰
오명호, 최홍섭, 김창휘, 이상주
순천향의과대학 소아과학교실
We took clinical study for 47 cases of Reye syndrome at S.C.H. University Hospital during last 8 years from Jan:, 1979 to Dec., 1986. The results obtained were as follows; 1) There was no significant difference in annual incidence and the seasonal incidence was highest in sumer and autumn. 2) The sex ratio of male to female was 1:1.4. 3) Among 47 cases, 34 cases (72.3%) were under 1 year of age. 4) Of the 47 cases, the preceeding illnesses were upper respiratory infection in 34 cases (72.2%), gastroenteritis in 5 cases (10.6%), upper respiratory infection with gastroenteritis in 5 cases (10.6%), pneumonia in 2 cases (4.3%), and chicken pox in 1 case (2.1%). 5) The manin clinical symptos were nausea and vomiting (80.9%), fever (74.5%), hyperventilation (59.6%), and hepatomegaly (48.9%). 6) The mortality was high in patients with elevated serum ammonia (≧ 300 ug/dl) and prolonged Prothrombin time ((≧ 14 sec). 7) According to Lovejoy’s classificatin, 17 cases (38.3%) were in stage III and IV on the admission. The higher the stage, the higher the mortality. 8) The overall mortality rate was 44.7%.
Key Words: Reye syndrome.

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