Urinary Red Blood Cell Morphology in Hematuria. |
Hong Jin Lee1, Chang Yeon Lee1, Hae Il Cheong1, Yong Choi1, Kwang Wook Ko1, Myung Hee Park2 |
1Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea 2Department of Clinical Pathology, College of Medicine, Seoul National University, Seoul, Korea |
혈뇨의 감별진단을 위한 소변내의 적혈구형태에
관한 연구 |
이홍진1, 이창연1, 정해일1, 최용1, 고광욱1, 박명희2 |
1서울대학교 의과대학 소아과학교실 2서울대학교 의과대학 임상병리학교실 |
Received: 7 June 1988 • Accepted: 25 July 1988 |
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Abstract |
We have studied morphological alterations in urinary RBC as a tool for the differential diagnosis
of hematuria in children, that is, differentiation of glomerular bleeding from nonglomerular bleeding,
and the results were as follows;
1) Urinary RBCs from glomerular diseases showed higher rate of dysmorphism (84.3±16.8%), and
those from nonglomerular diseases did lower one (15.2 ±12.9%) with phase contrast microscopic
examination.
2) Simple light microscopic examination after Wright’s staining revealed nearly same results with
phase contrast microscopic examination.
3) Accordingly, higher than 60% of dysmorphism for glomerular bleeding and lower than 30% for
nonglomerular bleeding could be proposed as discriminating levels with sensitivity of higher than 80
% and specificity of higher than 95%.
4) Since, however, 6 children with glomerular diseases showed low rate of dysmorphism during
acute stage with massive hematuria, regular follow-up examinations for 1—2 weeks should be
obtained before imprudent interpretations.
In conclusion, the morphological examination of urinary RBC is a simple and accurate method for
differentiating glomerular bleeding from nonglomerular bleeding in patients with hematuria. This
examination can be done with simple light microscope after Wright*s staining as accurately as with
phase contrast microscope. |
Key Words:
Urinary RBC morphology, Phase contrast microscope, Wright's staining, Hematuria |
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