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A Clinical Study on Patients with Sydenham's Chorea.

Journal of the Korean Pediatric Society 1989;32(7):1017-1022.
Published online July 31, 1989.
A Clinical Study on Patients with Sydenham's Chorea.
Jae Il Sohn, Young Sik Kim, Yong Seung Whang
Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea
Sydenham 무도증의 임상적 관찰
손재일, 김영식, 황용승
서울대학교 의과대학 소아과학교실
Received: 28 November 1988   • Accepted: 13 December 1988
Abstract
A clinical study was performed on 23 patients of Sydeham’s chorea in the children who admitted to the pediatric department of SNUH from Jan. 1980 to Dec. 1987. The results were as follows: 1) Among 316 patients with rheumatic fever, 10 patients (3%) had a chorea. 2) The age at onset of chorea ranged from 8 to 16 years. 3) The ratio of female to male was 1.9 : 1 Fifteen patients were female, 8 patients male. 4) In type, 13 patients (57%) had “pure” chorea and 10 patients (43%) had evidence of rheumatic fever. Twenty-two patients (96%) had a generalized chorea and 1 patient (4%) hemichorea. 5) In manifestations of rheumatic fever, 7 patients (70%) had a carditis. 6) In severity, it was mild in 4 patients (17%), moderate in 8 patients (35%), and severe in 11 patients (48%). 7) In duration of chorea, 11 patients (64%) were ranged from 1 month to 6 months, 2 patients (12 %) within 12 months, 2 patients (12%) within 24 months and 2 patients (12%) over 24 months. 8) There was no recurrence. 9) Therapy included haloperidol in 18 patients (78%), valium, chlorpromazine, predinisolone, and diphenylhydantion. In duration of drug therapy, 12 patients (70%) were within 3 months. 10) The EEG findings were abnormal in 5 of 9 patients, (56%) diffuse slowings in 3 patients, and focal slowings in 2 patients. 11) There was a suicidal attack in 1 patient.
Key Words: Sydenham’s Chorea


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