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Two Cases of Goitrous Hypothyroidism in Siblings.

Journal of the Korean Pediatric Society 1990;33(1):129-134.
Published online January 31, 1990.
Two Cases of Goitrous Hypothyroidism in Siblings.
Kwang Ok Lee, Hwa Il Kwag, Hoon Kook, Young Youn Choi, Tai Joo Hwang
Department of pediatrics, Chonnam University Hospital, Kwang Ju, Korea
남매에서 발생한 갑상선종성 갑상선기능저하증 1례
이광옥, 곽화일, 국훈, 최영륜, 황태주
전남대학교 의과대학 소아과학교실
Received: 15 June 1989   • Accepted: 15 June 1989
The authors experienced two cases of goitrous hypothyroidism in siblings. The etiology was considered to be defect of iodide organification in steps of thyroxine synthesis. The diagnosis was made on the basis of history, clinical features, thyroid function test, thyroid scanning, ultrasonogram and perchlorate discharge test. We report these cases with a review of related literatres.
Key Words: Goitrous hypothyroidism, defect of iodide organification

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