Glucose-6 Phosphate Dehydrogenase Deficiency.

Lee, Meen Jai; Lee, Sang Eun; Lee, Dong Whan; Lee, Sang Jhoo; Park, Sang Chul

Original Article

Journal of the Korean Pediatric Society 1990;33(2):212-219.
Published online February 28, 1990.

Glucose-6 Phosphate Dehydrogenase Deficiency.

Meen Jai Lee¹, Sang Eun Lee¹, Dong Whan Lee¹, Sang Jhoo Lee¹, Sang Chul Park²

¹Department of Pediatrics, College of Medicine, Soon Chun Hyang University, Seoul, Korea
²Department of Biochemistry, College of Medicine, Seoul National University, Seoul, Korea

Glucose-6-Phosphate Dehydrogenase 결핍증 1례

이민재^¹^, 이상은^¹^, 이동환^¹^, 이상주^¹^, 박상철^²

^¹순천향대학 의학부 소아과학교실
^²서울대학교 의과대학 생화학교실

Received: 29 June 1989 • Accepted: 19 September 1989

Abstract

Glucose-6-phosphate dehydrogenase(G-6PD) deficiency is the most common disease-producing enzyme deficiency of human beings, but extremely rare in Korea. Four well-characterized clinical syndromes are recognized: acute, oxidative stress(drug or infection) induced hemolytic anemia; neonatal hyperbilirubinemia; favism and chronic nonspherocytic hemolytic anemia. We have experi- enced a case of G-6PD deficiency in child associated with chronic hemolytic anemia and exacerba- tions of hemolysis by infection and drug administration. We made a brief review of related literature.

Key Words: G-6PD deficiency