Journal of the Korean Pediatric Society 1990;33(8):1155-1158.
Published online August 31, 1990.
Two Cases of Cerebral Gigantism (Sotos Syndrome).
Hee Jeung Ahn, Young Tae Kim, In Hoon Seol, Jeh Hoon Shin
Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea
Cerebral Gigantism (Sotos 증후군) 2 례
안희정, 김영태, 설인준, 신재훈
한양대학교 의과대학 소아과학교실
Received: 8 February 1990   • Accepted: 9 May 1990
Cerebral gigantism, the condition described by Sotos et al in 1964, consists of excessively rapid growth rating from infancy followed by a normal growth rate, acromegalic features, and a non- progressive neurological disorder manifested by clumsiness. The etiology of cerebral gigantism is not clear. Increased growth hormone levels have not been documented and somatomedin activity was found to be within normal range as yet reported. We experienced two cases of cerebral gigantism in 1 10/12 and 7 year old girls with a brief review of literatures.
Key Words: Cerebral Gigantism

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