A clinical study on neonatal seizures. |
Bong Sik Kong, Ri Sa Lee, Sang Kyu Park, Ho Jin Park |
Department of Pediatrics, Seoul Red Cross Hospital, Seoul, Korea |
신생아 경련의 임상적 고찰 |
공봉식, 이리사, 박상규, 박호진 |
서울적십자병원 소아과 |
Received: 12 July 1990 • Accepted: 17 October 1990 |
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Abstract |
Clinical observation were made on 57 cases of neonatal seizure who were admitted to the Depart-
ment of pediatrics, Seoul Red Cross Hospital during the period of 7 years from Jan. 1983 to Dec. 1989.
The results were as follows:
1) According to the type of delivery of neonates which showed neonatal seizure, normal vaginal
delivery were 41 cases (71.9%), C-section delivary 11 cases (19.3%) and breech delivery were 5 cases
(8.8%).
2) According to the gestational period, the frequency of preterm baby was 19.3% and of postterm
baby was 5.3% and the majority of neonates were included to the term baby.
3) The most frequent cause of neonatal seizure was hypoxic-ischemic brain damage (36.8%), and
followed by sepsis with or without meningitis (22.8%), intracranial hemorrhage (14%), hypoglycemia
(5.3%), hyponatremia (5.3%) and kemicterus (3.5%) in order of frequency.
4) The onset of 12 cases (21%) of neonatal seizure appeared within 24hours of life, 11 cases (19.3%)
in 2nd day and 5 cases (8.8%) in 3rd day. Two-third of neonatal seizure occurred within 7days of life.
5) The most frequent type of neonatal seizure was generalized tonic (54.4%) and followed by subtle
(36.8%), multifocal clonic (5.3%) and myoclonic (3.5%) in order of frequency.
6) The brain CT were performed in 10 cases. They showed intracranial hemorrhage in 3 cases,
frontal edema in 2 cases, massive hydrocephalus and ventriculitis, subdural hygroma in 1 case and
there were no evidence of abnormality in 3 cases.
7) The result of EEG finding was normal (47.1%) and abnormal (52.9%).
8) As the result of treatment, 32 cases (56%) of neonatal seizure were discharge in the state of
improvement, 19 cases (33.3%) were discharged against medical advice and 6 cases (10.5%) expired.
9) The most favorable outcome resulted from neonate with medical disturbance (improved in all
cases) and the worst outcome resulted from neonate with intracranial hemorrhage (improved in 25%). |
Key Words:
Neonatal seizures |
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