| The clinical study on MCLS. |
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Young Sun Ko, Ji Sun Cho, Hong Bae Kim, Ji Sub Oh |
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Department of Pediatrics, Wallace Memorial Baptist Hospital, Pusan, Korea |
| MCLS에 관한 임상적 고찰 |
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고영선, 조지선, 김홍배, 오지섭 |
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왈레스기념 침례병원 소아과 |
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Received: 9 July 1990 • Accepted: 26 September 1990 |
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| Abstract |
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Forty six children with mucocutaneous lymph node syndrome were diagnosed and treated through
admission at the Department of Pediatrics, Wallace Memorial Baptist Hospital from January 1987 to
January 1990. Ther were investigated for clinical pattern and laboratory correlations.
The results were as follows:
1) Most patients (95.7%) were under four years of the age.
2) The ratio of male to female was 1.6:1.
3) Seasonal incidence was high in February, June and July, respectively.
4) The incidence of principal symptoms were fever lasting 8.4±2.6 day (100%) bilateral conjun-
ctival injection 995.7%), skin rash (91.3%), red fissured lips (82.6%), stawberay tongue (80.4%),
desquamation (80.4%), cervical lymphadenopathy (52.2%), and induration of palm and sole (47.8%).
The incidence of other symptons were cough and coryza (58.7%), vomiting (32.6%) diarrhea (34.
8%) & jaundice (13.0%). The associated diseases were one case of pericardial effusion, two cases of
GB hydrops and seven cases of pneumonia.
5) The abnormal laboratory findings observed were anemia (19.6%), leukocytosis (97.8%) throm-
bocytosis (91.3%), increases ESR (100%)，positive CRP (100%), pyuria (50.0%), increased SGOT (31.
8%), increased SGPT (50.0%), increased LDH (37.2%)，increased CPK (23.7%) & increased tz2globulin
(87.1%). The peak thrombocytosis appeared on the 10-16 days after onset of the disease & returned
to normalization on 16-24 days after onset of the disease.
6) The abnormal findings of EKG were found in 78.3% of the patients and were prolonged QTc
interval (56.5%), low R wave in VI,6 (32.6%), ST-T wave change (26.0%), prolonged PR interval (6.
5%) and Flat T wave in V5, 6 (4.3%).
7) The M-mode echocardiographic abnormality consisted of increase in ratio of the left posterior
wall to septal excursion in (4.3%), decrease of fractional shortening in (32.6%), increase of systolic
time interval in (19.6%). The 2D echocardiographic abnormalities consisted of coronary aneurysm
(23.9%), pericardial effusion (2.2%) & grade I /IV mitral regurgitation (10.9%). The sites of coro-
nary aneurysm were left coronary artery (100%) and combination of left coronary artery & right
coronary artery (18.1%).
8) Duation of fever, positive CRP & WBC count were statistically higher in patients with coronary
aneurysm than in patients without coronary aneurysm. |
| Key Words:
Mucocutaneous lymph node syndrome |
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