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Predictors of neurologic handicap in hypoxic ischemic encephalopathy.

Journal of the Korean Pediatric Society 1991;34(4):473-479.
Published online April 30, 1991.
Predictors of neurologic handicap in hypoxic ischemic encephalopathy.
Seung Tae Kim, Gui Ran Kim, Byung Hak Lim, Sang Geel Lee, Im Ju Kang
Department of Pediatrics, Fatima Hospital, Taegu, Korea
신생아 저산소성 허혈성 뇌증의 예후에 관련되는 인자들
김승태, 김귀란, 임병학, 이상길, 강임주
대구파티마병원 소아과
Received: 31 July 1990   • Accepted: 10 November 1990
Abstract
Retrospective follow up studies were done in 52 term infants who were treated at the nursery in Taegu Fatima Hospital, for clinical evidence of Hypoxic ischemic enecphalopathy (stage II). All children were followed for a minimum of 6 months. Factors that significantly correlated with prognosis included 5-minute Apgar scores, the age at the onset of the seizures, the EEG and the initial brain CT. (1) Of seven with the severe asphyxia (Apgar score 0 〜3》,six showed the abnormal neurologic handicap on follow up study (p<0.01). (2) Of eleven with the occurrence of seizure within 12 hours, seven showed the abnormal neurologic handicap (p<0.01). (3) Of fifteen with the abnormal EEG finding, ten shwoed the abnormal neurologic handicap (p< 0.01). (4) Of sixteen with the abnormal brain CT finding, eleven showed neurologic handicap on follow up study. Especially nine with the extensive area of hypodensity of the white and gray matter were severely handicapped (p<0.01).
Key Words: Hypoxic ischemic encephalopathy, Predictors of Neuroloogic handicap


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