Journal of the Korean Pediatric Society 1991;34(11):1598-1604.
Published online November 30, 1991.
a case of type II lissencephaly; Walker-Earburg syndrome.
Ae Yong Kim, Jung Ho Lee, Yong Sub Kim, Kyeng Sook Cho, Jong Dai Jo
Department of Pediatrics, Maryknoll Hospital, Pusan, Korea
II형 Lissencephaly; Walker-Warburg 증후군 1례
김애영, 이정호, 김용섭, 조경숙, 조종대
메리놀병원 소아과
Received: 7 May 1991   • Accepted: 10 July 1991
Abstract
Lissencephaly is a rare abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface. Three types of lissencephaly are recognized. Type I is characterized by microcephaly and dysmorphic facies. Type II usually lacks characteristic facies but exhibits macrocephaly from hydrocephalus, eye anomaly, and/or congenital muscular dystrophies. Type III is characterized by microcephaly without any characteristic dysmorphic facial features. We have experienced a case of Type II lissencephaly (Walker-Warburg syndrome). In this case lissencephaly, hydrocephalus, hypoplasia of corpus callosum, hypoplasia of septum pellucidum, retinal dysplasia, optic atrophy, nystagmus was noticed. So we presented this case with a review of refer- ential literatures.
Key Words: lissencephaly, Walker-Warburg syndrome




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