| Epidemiology of anaphylaxis in Korean children |
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Dae Hyun Lim1 |
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Correspondence:
Dae Hyun Lim,
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| Abstract |
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Anaphylaxis is an acute systemic reaction caused by IgE-mediated immunological release of mediators from mast cells and
basophils to allergenic triggers, such as food, insect venoms, and medications. An alternative definition was recently proposed
as follows: anaphylaxis is a "condition caused by an IgE mediated reaction" that is "often life threatening and almost always
unanticipated." The reaction can be severe enough to lead to the rapid onset of symptoms, including dizziness, upper airway
occlusion, bronchial constriction, hypotension, urticaria, cardiovascular arrhythmias and possible cardiac arrest. The incidence
or prevalence of anaphylaxis in Korean pediatrics has not known. Thus, Epidemiology of Anaphylaxis in Pediatrics based on
the data from Korean Health Insurance Review and Assessment Service (KHIRA) from 2001 to 2007 and questionnaire to
the member of Korean Academy of Pediatric Allergy and Respiratory Disease (KAPARD) who are working at the training hospitals
was studied. The incidence of anaphylaxis under age 19 is 0.7-1.0 per 100,000 year-person. The causes of anaphylaxis
based on data from KHIRA were unknown (61.7%), food (24.9%), medications (12.4%), and serum (1.0%). |
| Key Words:
Anaphylaxis |
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