Korean Journal of Pediatrics 2010;53(1):106-110.
Published online January 15, 2010.
A case of hippocampal sclerosis diagnosed as cortical dysplasia due to preoperative brain MRI finding
Jun Seok Lee1, Kyo Ryung Kim1, Jeong Tae Kim1, Min Jung Choi1, Young Mock Lee1, Heung Dong Kim1, Joon Soo Lee1, Dong Seok Kim2, Tae Seong Kim3
1Department of Pediatrics, Severance Children`s Hospital, Yonsei University College of Medicine, Seoul, Korea
2Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea
3Department of Pathology, Yonsei University College of Medicine, Seoul, Korea
수술 전 뇌 자기공명 영상에서 겉질 형성이상증 소견 보였으나 수술 후 병리학적으로 확인된 해마경화증 1례
이준석1, 김교륭1, 김정태1, 최민정1, 이영목1, 김흥동1, 이준수1, 김동석2, 김태승3
1연세대학교 의과대학 소아과학교실
2연세대학교 의과대학 신경외과학교실
3연세대학교 의과대학 병리학교실
Correspondence: 
Joon Soo Lee, Tel: +82.2-2228-2063, Fax: +82.2-393-9118, Email: joonsl96@yuhs.ac
Abstract
Hippocampal sclerosis (HS) is one of the most common features of intractable temporal lobe epilepsy. Generally it can be identified through brain magnetic resonance imaging (MRI) with high degree of sensitivity and specificity. Typical brain MRI findings of HS are hippocampal atrophy with hyperintense signal confined to the lesion. On the other hand cortical dysplasia exhibits blurring of the gray-white matter junction and abnormal white matter signal intensity. We present a case where preoperative brain MRI strongly suggested the presence of diffuse cortical dysplasia in the left temporal lobe but postoperative pathology revealed the temporal lesion to be unremarkable except for hippocampal sclerosis.
Key Words: Hippocampus, Cortical dysplasia, Epilepsy, Surgery, MRI


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