Korean Journal of Pediatrics 2009;52(1):14-21.
Published online January 15, 2009.
Neurodevelopmental outcomes of very low birth weight infants and extremely low birth weight infants in Korea, 1984-2008
In Kyung Sung
Department of Pediatrics, St. Mary`s Hospital, Catholic University of Korea, College of Medicine, Seoul, Korea
극소 및 초극소저체중 출생아의 신경발달 예후(1984-2008년)
성인경
가톨릭대학교 의과대학 소아과학교실
Correspondence: 
In Kyung Sung, Email: sinky@catholic.ac.kr
Abstract
Neurodevelopmental outcomes of very low birth weight infants (VLBWI) and extremely low birth weight infants (ELBWI) in Korea on 14 reports from 1984 to 2008 were analyzed. Follow-up rates were varied from 42.9% to 90.2%. Duration of follow-up ranged from 4 months to 5 years. The prevalence of cerebral palsy (CP) of VLBWI was as follows: 4.3-5.3% in 1980s, 7.1-9.1 % in 1990s and 3.6-15.6% in 2000s. CP was noted in 8.2-30.8% of ELBWI on studies reported in 2000s. Delayed Mental development was diagnosed in 2.0-17.9% of VLBWI and in 20.4-30.8% of ELBWI. Sensory impairments such as hearing loss or visual deficit were reported in 3.1-3.6% of VLBWI and 0.0-10.0% of ELBWI. Seizure disorder was reported in 5.3% of VLBWI by one report. No reports for minor neurodevelopmental dysfunctions in VLBWI and ELBWI were found from 1984 to 2008. It is necessary to establish basic protocols and nationwide systems for long-term follow-up study to obtain valuable data.
Key Words: Neurodevelopmental outcome, Follow-up, Infant, Very low birth weight, Extremely low birth weight, Newborn, Korea


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