Korean Journal of Pediatrics 2008;51(6):640-645.
Published online June 15, 2008.
Clinical manifestations patterns of allergic disease in Korean children under the age of 6 : multi-center study
Dong Il Kim1, Hyeon Jong Yang1, Young Mean Park2, Yeong Ho Rha3, Ji Tai Choung4, Bok Yang Pyun1
1Department of Pediatrics, College of Medicine, Soonchunhyang University, Seoul, Korea
2Department of Pediatrics, College of Medicine, Konkuk University, Seoul, Korea
3Department of Pediatrics, College of Medicine, Kyunghee University, Korea University , Seoul, Korea
4Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea
다 기관 설문 조사를 통한 알레르기 질환의 연령별 임상 양상
김동일1, 양현종1, 박용민2, 나영호3, 정지태4, 편복양1
1순천향대학교 의과대학 소아과학교실
2건국대학교 의과대학 소아과학교실
3경희대학교 의과대학 소아과학교실
4고려대학교 의과대학 소아과학교실
Correspondence: 
Bok Yang Pyun, Email: bypyun@hosp.sch.ac.kr
Abstract
Purpose
: It is widely known that allergic diseases progress through an allergic march. However, there have not been any recent reports in Korea on how the diseases progress.
Methods
: Parents who visited one of the Pediatric Allergy Clinics of four university hospitals in Seoul with a child under the age of 6 years during the period from May 1-30, 2006 were asked to complete a questionnaire.
Results
: A total of 229 parents answered the questionnaire about their children, of which 122 were male and 107 were female. The most common allergic disease before 2 years of age was atopic dermatitis (79%). Meanwhile, in 2- to 4-year age group, allergic rhinitis (38%) and asthma (37%) were predominant. The most common allergic disease in the 4- to 6-year age group was asthma (72%), followed by allergic rhinitis (64%). Seventy-three percent of the children had a family history of allergic disease, most often in the fathers (39%). Among patients with allergic rhinitis, 50% had experienced asthma in their earlier days and 30% had experienced atopic dermatitis. In addition, 57% of the children with asthma had suffered from atopic dermatitis. Parents believed that asthma was the most serious allergic disease.
Conclusion
: In the present study, allergic disease showed a tendency to march from atopic dermatitis to asthma and then to allergic rhinitis. Early diagnosis and treatment of atopic dermatitis is, therefore, considered important for prevention of the allergic march.
Key Words: Allergic march, Questionnaire, Multicenter study


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