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Two cases of central nervous system complications caused by Mycoplasma pneumoniae infection

Korean Journal of Pediatrics 2008;51(5):533-537.
Published online May 15, 2008.
Two cases of central nervous system complications caused by Mycoplasma pneumoniae infection
Shin Mi Kim, Ji Seung Heo, Eun Jung Shim, Dae Hyoung Lee, Do Jun Cho, Dug Ha Kim, Ki Sik Min, Ki Yang Yoo
Department of Pediatrics, College of Medicine, Hallym University, Korea
Mycoplasma pnuemonia 감염에 의한 중추신경계 합병증 2례
김신미, 허지승, 심은정, 이대형, 조도준, 김덕하, 민기식, 유기양
한림대학교 의과대학 소아과학교실
Correspondence: 
Ki Sik Min, Email: ksmin@hallym.or.kr
Abstract
Mycoplasma pneumoniae (M. pneumoniae) infection causes a wide variety of clinical manifestations in children and young adults, the main one being pneumonia. M. pneumoniae is transmitted from person to person by infected respiratory droplets. Symptoms caused by M. pneumoniae infection can be divided into those involving the respiratory tract, and those caused by extrapulmonary disease. M. pneumoniae infections may cause central nervous system (CNS) complications춛ith encephalitis being the most frequent춁nd stroke being a rare complication. The pathogenesis of the CNS disease is unclear; possibilities include direct infection and an immune-mediated reaction. We present two cases of CNS complications subsequent to infection with M. pneumoniae; both cases had convincing evidence of preceding M. pneumoniae respiratory disease with no evidence of viable M. pneumoniae in the cerebrospinal fluid. We report cases of encephalitis and stroke following a recent M. pneumoniae infection.
Key Words: Mycoplasma pneumoniae, Central nervous system, Encephalitis, Stroke


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