Korean Journal of Pediatrics 2007;50(11):1078-1084.
Published online November 15, 2007.
Pulse wave velocity and ankle brachial index in obese adolescents
Ji Hye Kim, Hee Sun Koo, Young Mi Hong
Department of Pediatrics, School of Medicine, Ewha Womans University, Seoul, Korea
비만 청소년에서 맥파 속도와 발목 상완 동맥압 지수에 대한 연구
김지혜, 구희선, 홍영미
이화여자대학교 의과대학 소아과학교실
Young Mi Hong, Email: hongym@chollian.net
: The prevalence of childhood obesity has doubled over the last 30 years. Obesity-associated sequelae in the vasculature begins in the early stages of life. The purpose of this study was to investigate how pulse wave velocity (PWV) and ankle brachial index (ABI) change with height, weight and body mass index (BMI) in obese adolescents.
: Seventy-nine obese adolescents (group 1: 85th BMI<95th percentile, n=40; group 2 (BMI 95th percentile, n=39) were included. The control group(group 3) included 99 healthy adolescents. Brachial- ankle (ba) PWV and ABI were estimated with blood pressure from four extremities. Heart rate (HR), and pre-ejection period/ejection time (PEP/ET) were also estimated. BMI was calculated from individual height and weight. Linear regression analysis was performed to evaluate the correlations between BMI and PWV.
: Blood pressure and baPWV were significantly higher in group 2, compared to either group 1 or group 3. However, there was no significant difference in ABI, HR and PEP/ET between the groups. PWV showed linear correlation with both BMI and body weight.
: Obesity was associated with higher arterial stiffness in adolescents, which was demonstrated by an increase in PWV. There was no significant correlation between obesity and ABI.
Key Words: Obesity, Cardiovascular diseases, Adolescent, Blood pressure

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