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Two cases of Chryseobacterium meningosepticum infection in a neonatal intensive care unit

Korean Journal of Pediatrics 2007;50(7):698-701.
Published online July 15, 2007.
Two cases of Chryseobacterium meningosepticum infection in a neonatal intensive care unit
Hye Sun Yoon
Department of Pediatrics, School of Medicine, Eulji University, Seoul, Korea
신생아 중환자실에서 발생한 Chryseobacterium meningosepticum 감염 2례
윤혜선
을지대학교 의과대학 을지병원 소아과
Correspondence: 
Hye Sun Yoon, Email: yhs3211@eulji.ac.kr
Abstract
We report on two premature infants who developed nosocomial infection caused by Chryseobacterium meningosepticum in a neonatal intensive care unit (NICU). One premature infant developed sepsis, meningitis, and hydrocephalus, and was treated successfully with ciprofloxacin plus trimethoprim-sulfamethoxazole combination therapy for 4 weeks and with a ventriculoperitoneal shunt. The other premature infant, who was in a chronically debilitated state, had infection that had colonized only in the respiratory tract but had no clinical signs for 66 days. Extensive environmental surveillance demonstrated that the suction bottle apparatus was the source of infection. We prevented the spread of infection by closing the NICU temporarily, isolating the patients early in their infection, and eradicating the source of infection source.
Key Words: Chryseobacterium meningosepticum, Ciprofloxacin, Neonatal intensive care unit


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