Korean Journal of Pediatrics 2007;50(6):580-584.
Published online June 15, 2007.
A case of childhood relapsing/remitting multiple sclerosis and interferon β-1b treatment in a Korean patient
Hyun Seok Kim, Won Deok Lee, Jun Hwa Lee, Kyung Lae Cho
Department of Pediatrics, College of Medicine, Sungkyunkwan University Masan Samsung Hospital, Masan, Korea
소아 재발/완화형 다발성 경화증 환자에서 인터페론 베타 1b 치료 1례
김현석, 이원덕, 이준화, 조경래
성균관대학교 의과대학 마산삼성병원 소아과
Correspondence: 
Jun Hwa Lee, Email: ljh3643@hanmail.net
Abstract
Multiple sclerosis (MS) is a demyelinating disorder that affects discrete areas of the CNS, including the optic nerves, in a quite variable relapsing-remitting fashion over a prolonged period of time. Although MS is usually considered to be a disease that affects peoples in early to middle adulthood, children do develop multiple sclerosis. The frequency of MS onset before the age of 15 years is 2.7-5% of all cases, while MS onset during infancy and early childhood was observed to be 0.2- 0.7% of all cases. We report here on a Korean case of a relapsing-remitting MS female child who was treated with four rounds of intravenous methylpredinsolone pulse therapy and preventive Interferon-β-1b (Betaferon ).
Key Words: Multiple Sclerosis, Optic neuritis, Interferon-β-1b (Betaferon )


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