Topiramate can reduce the number of episodic attacks in
cyclic vomiting syndrome : a case report |
Mi-Sun Yum1, Keun Wook Bae1, Su Jeong You2, Tae Sung Ko1 |
1Department of Pediatrics, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea 2Department of Pediatrics, Epilepsy Center, College of Medicine, Inje University, Seoul, Korea |
Topiramate 투여로 호전된 주기성 구토증 1례 |
염미선1, 배근욱1, 유수정2, 고태성1 |
1울산대학교 의과대학 소아과학교실 2인제대학교 의과대학 소아과학교실 |
Correspondence:
Tae Sung Ko, Email: tsko@amc.seoul.kr |
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Abstract |
Cyclic vomiting syndrome (CVS) is a paroxysmal, recurrent vomiting disorder of unknown pathophysiology and target organ. It has been hypothesized that CVS shares the same mechanism as migraine. We describe here a 5-year-old boy with CVS characterized by episodic vomiting attacks. These recurrent vomiting episodes began at 3 years of age, occurred every month and lasted for 5 days at a time. At the time of admission, no abnormal physical or neurological findings were observed and laboratory findings, including brain MRI and endoscopic examination, revealed nothing specific. The vomiting episodes were self-limited but recurrent and severely interrupted his daily life. When this patient was treated with topiramate, he showed a marked increase of symptom-free periods. |
Key Words:
Vomiting , Topiramate , Migraine , Child |
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