| Comparison of Epileptic Seizures between Preterm and Term-born Epileptic Children with Periventricular Leukomalacia |
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Hee Jeong Jeong, Eun Sil Lee, Han Ku Moon |
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Department of Pediatrics, Collage of Medicine, Yeungnam University, Daegu, Korea |
| 뇌실 주위 백질연화증이 있는 간질 환아에서 조산 및 만삭 출산군 간의 간질 발작 유형의 비교 |
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정희정, 이은실, 문한구 |
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영남대학교 의과대학 소아과학교실 |
Correspondence:
Han Ku Moon, Email: hkmoon@med.yu.ac.kr
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| Abstract |
Purpose
: This study compares the first epileptic seizures between preterm and term-born children with periventricular leukomalacia and epilepsy.
Methods
: From 108 cases having lesions of high signal intensity around the ventricles in T2 weighted imaging of a brain magnetic resonance study, we selected 37 cases that showed epileptic seizures two times or more and divided them into the group of preterm-born(27 cases) and term- born children(10 cases). A retrospective study was made by comparing the two groups with regard to age, type of the first epileptic seizures, EEG findings and responsiveness to anticonvulsants.
Results
: The age of the first epileptic seizure was 22.2?8.3 months in the preterm-born group and 26.9?1.1 months in the term-born group(P=0.505). As for the first epileptic seizure, 11 out of the 27 cases in the preterm-born group had infantile spasms. Out of the 10 cases in the term-born group, 7 had complex partial seizures. In the preterm group, hypsarrhythmias were found in 11 cases, focal epileptiform discharges in 6 cases. In term-born group, focal epileptiform discharges were found in 5 cases but no epileptiform discharge was found in 3 cases. Intractable epilepsies were diagnosed in 6 cases and all of them belonged to the preterm-born group.
Conclusion
: More severe epilepsies such as infantile spasm and intractable epilepsies seem to be more common in preterm-born epileptic children with PVL as well as more severely abnormal EEG finding compared to term-born epileptic children. |
| Key Words:
Periventricular leukomalacia , Fullterm and preterm infant , Epilepsy |
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