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A Case of Neonatal Lupus with Abnormal Liver Function Test and Skin Lesion

Korean Journal of Pediatrics 2005;48(1):85-87.
Published online January 15, 2005.
A Case of Neonatal Lupus with Abnormal Liver Function Test and Skin Lesion
Ju-Young Chung, Myoung Jae Chey
Department of Pediatrics, Sanggyepaik Hospital, Inje University College of Medicine, Seoul, Korea
피부 병변과 간기능 이상이 동반된 신생아 루푸스 1례
정주영, 최명재
인제대학교 의과대학 상계백병원 소아과
Correspondence: 
Ju-Young Chung, Email: pedchung@sanggyepaik.ac.kr
Abstract
Neonatal lupus(NL) is characterized by typical clinical features and the presence of maternal auto- antibodies. The principal serologic markers of NL are anti-Ro/SSA or anti-La/SSB maternal auto- antibodies, which are transferred across the placenta and can be detected for the first few months of the affected child. The major clinical manifestations are cardiac disease, notably congenital heart block, and cutaneous lupus lesions. Hepatobiliary disease is relatively rare clinical manifestation of NL. We experienced a case of NL with abnormal liver function test and skin lesion.
Key Words: Lupus, Neonate


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