Journal of the Korean Pediatric Society 2003;46(12):1279-1282.
Published online December 15, 2003.
A Therapeutic Experience of Congenital Bilateral Neuroblastoma
Yeon Kyong Seo1, Heung Sik Kim1, Kun Young Kwon2, Hee Jung Lee3, Hong Hoe Koo4
1Department of Pediatrics,School of Medicine, Keimyung University, Daegu, Korea
2Department of Pathology, School of Medicine, Keimyung University, Daegu, Korea
3Department of Radiology, School of Medicine, Keimyung University, Daegu, Korea
4Department of Pediatrics, School of Medicine, Sungkyunkwan University, Seoul, Korea
선천성 양측성 신경모세포종의 치료경험 1례
서연경1, 김흥식1, 권건영2, 이희정3, 구흥희4
1계명대학교 의과대학 소아과학교실
2계명대학교 의과대학 병리과학교실
3계명대학교 의과대학 진단방사선과학교실
4성균관대학교 의과대학 소아과학교실
Correspondence: 
Heung Sik Kim, Email: kimhs@dsmc.or.kr
Abstract
Neuroblastoma is the most common intraabdominal malignant tumor of childhood, with 40% arising from the adrenal gland. Bilateral adrenal involvement from synchronous development or metastatic spread of tumor is rarely seen in children with neuroblastoma. The patient was born with a spontaneous vaginal delivery. Birth weight was 3,200 g. Fetal ultrasonography showed a left adrenal cystic mass. At two weeks of age, she was admitted due to a massive abdominal distension and tachypnea. Percutaneous ultrasonography guided biopsy of the left adrenal mass was performed. The result of the biopsy was neuroblastoma. Vincristine and cyclophosphamide were administerd intravenously and 450 cGy of irradiation was added. Left adrenalectomy was accomplished and postoperative course was uneventful. The patient received cancer chemotherapy with a combination of carboplatin, ifosfamide and VP-16 and is now being followed up for three months. We have experienced a case of congenital bilateral neuroblastoma and report the case with brief review of related literatures.
Key Words: Congenital neuroblastoma, Bilateral neuroblastoma


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