| A Case of Acute Pancreatitis in a Neuroblastoma Patient after
Retinoic Acid Therapy |
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Yoo Jin Jeong1, Yeon Kyong Seo1, Heung Sik Kim1, Hee Jung Lee2 |
1Department of Pediatrics, School of Medicine, Keimyung University, Taegu, Korea
2Department of Diagnostic Radiology, School of Medicine, Keimyung University, Taegu, Korea |
| 신경모세포종 환아에서 레티노익산 치료 중 발생한급성 췌장염 1례 |
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정유진1, 서연경1, 김흥식1, 이희정2 |
1계명대학교 의과대학 소아과학교실
2계명대학교 의과대학 진단방사선학교실 |
Correspondence:
Heung Sik Kim, Email: kimhs@dsmc.or.kr
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| Abstract |
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Retinoic acid has been used successfully as a differentiating agent in acute promyelocytic leukemia and neuroblastoma. However, some adverse effects have been recognized, such as headaches, dry skin and retinoic acid syndrome, a life threatening acute cardiorespiratory disorder. Acute pancreatitis with hyperlipidemia has rarely been reported. We experienced a case of acute pancreatitis with hyperlipidemia in a neuroblastoma patient after retinoic acid therapy for 21 months. Although the patient was ordered nothing by mouth and total parenteral nutrition was administrated, she died of disseminated intravascular coagulopathy and pulmonary hemorrhage, possibly because of oral intake during her recovery period. |
| Key Words:
Retinoic acid, Acute pancreatitis, Hyperlipidemia, Neuroblastoma |
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