Complications and Perinatal Factors According to the Birth Weight Groups in the Infants of Diabetic Mothers

Son, Kyung-Ran; Back, Hee-Jo; Cho, Chang-Yee; Choi, Young-Youn; Song, Tae-Bok; Park, Chun-Hak

Original Article

Journal of the Korean Pediatric Society 2003;46(5):447-453.
Published online May 15, 2003.

Complications and Perinatal Factors According to the Birth Weight Groups in the Infants of Diabetic Mothers

Kyung-Ran Son¹, Hee-Jo Back¹, Chang-Yee Cho¹, Young-Youn Choi¹, Tae-Bok Song², Chun-Hak Park³

¹Department of Pediatrics, Chonnam National University Medical School, Gwangju, Korea
²Department of Obstetric and Gynecology, Chonnam National University Medical School, Gwangju, Korea
³Department of Pediatrics, Seonam University Medical School, Namwon, Korea

당뇨병 산모아에서 출생 체중군에 따른 합병증 및 주산기 인자

손경란^¹^, 백희조^¹^, 조창이^¹^, 최영륜^¹^, 송태복^²^, 박천학^³

^¹전남대학교 의과대학 소아과학교실
^²전남대학교 의과대학 산부인과학교실
^³서남대학교 의과대학 소아과학교실

Correspondence:
Young-Youn Choi, Email: yychoi@chonnam.ac.kr

Abstract

Purpose
: This study was performed to compare complications and perinatal factors according to the birth weight groups in the infants of diabetic mothers(IDM).
Methods
: Three hundred and one singleton diabetic mothers and their babies of more than 30 weeks' gestational age admitted in the department of Pediatrics, Chonnam University Hospital from January 1996 to March 2002 were enrolled. Complications and perinatal factors were compared between large for gestational age(LGA) and appropriated for gestational age(AGA) infants.
Results
: Hypomagnesemia was observed in 37.5%, jaundice in 21.3%, hypoglycemia in 11.1%, hypocalcemia in 7.0%, and birth injury in 19.6%. Congenital anomaly was noted in 24.9% with cardiovascular anomaly most commonly. In the LGA group, the frequencies of jaundice, hypoglycemia, tachypnea, and birth injuries were higher, and the interventricular septum was thicker than the AGA group. In the LGA group, Cesarean section rate, maternal height, weight before pregnancy, weight gain during pregnancy, and the incidence of unawareness of gestational DM were significant compared with the AGA group.
Conclusion
: In the LGA group, the frequencies of jaundice, hypoglycemia, tachypnea, and birth injuries were higher, and the interventricular septum was thicker than the AGA group. In the LGA group, maternal height, weight before pregnancy and weight gain during pregnancy were larger, and the incidence of unawareness of gestational DM was higher compared with the AGA group. These results suggest that careful examination and management are needed to detect the high risk, pregnant DM mothers with possible LGA babies.

Key Words: Infants of diabetic mothers, Large for gestational age, Complication, Perinatal factors