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M-mode Echocardiographic Abnormalities in Infants of Diabetic Mothers

Journal of the Korean Pediatric Society 2001;44(8):881-885.
Published online August 15, 2001.
M-mode Echocardiographic Abnormalities in Infants of Diabetic Mothers
Myung Chul Hyun
Department of Pediatrics, School of Medicine, Kyungpook National University, Taegu, Korea
당뇨병 산모로부터 태어난 영아의M형 심에코 검사 이상소견
현명철
경북대학교 의과대학 소아과학교실
Abstract
Purpose
: The purpose of this study was to evaluate M-mode echocardiographic abnormalities in infants of relatively well controlled diabetic mothers and to determine the timing of spontaneous regression.
Methods
: Echocardiographic study was prospectively carried out in 9 neonates born to diabetic mothers(infants of diabetic mothers, IDM) and 6 newborn infants(control) matched for weight and age. And the study were repeated in 3 of 9 IDM(follow up) after 3 to 16 months. M-mode echocardiography included measurements of left and right ventricular free wall and interventricular septal thickness and ventricular diastolic and systolic dimensions; LV function is expressed as shortening fracion.
Results
: Interventricular septal thickness(0.56?.13 vs 0.32?.09) and STd/PWTd(2.04?.60 vs 1.19?.44) were significantly higher in infants of diabetic mothers than in control newborn infants. Follow up measurements showed regression of interventricular septal thickness(2.13?.58 vs 1.02?.66/M2) but no significant improvement in STd/PWTd(2.04?.60 vs 1.67?.25) compared with initial measurements.
Conclusion
: M-mode echocardiographic abnormalities including interventricular septal hypertrophy and high STd/PWTd were observed even in infants of relatively well controlled diabetic mothers and may persist for a somewhat longer period.
Key Words: Echocardiographic abnormalities, Infants of diabetic mothers, Spontaneous regression


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