| A Neonatal Case of Symptomatic Congenital Cytomegalovirus
Infection with Hearing Defect |
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Sung Jun Jang, Yoon Jung Cho, Sang Lak Lee, Joon Sik Kim, Tae Chan Kwon |
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Department of Pediatrics, School of Medicine, Keimyung University, Taegu, Korea |
| 청력 장애가 동반된 유증상 선천성 거대세포바이러스 감염 신생아 1례 |
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장성준, 조윤정, 이상락, 김준식, 권태찬 |
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계명대학교 의과대학 소아과학교실 |
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| Abstract |
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Cytomegalovirus(CMV) is one of the leading cause of intrauterine infections of man with an incidence ranging from 0.48% to 2.2% of all live births. Although the majority of CMV-infected newborns are clinically asymptomatic at birth, some will have signs of congenital infection : Intrauterine growth retardation, petechial or purpuric rash, microcephaly, anemia, thrombocytopenia, jaundice, hepatosplenomegaly and intracranial calcification. We experienced a case of symptomatic congenital CMV infection in a 1-day-old male who presented generalized petechiae, hepatosplenomegaly, anemia, thrombocytopenia. Urine PCR and viral culture for CMV were positive, and a brain CT revealed ventriculomegaly and periventricular calcification. And auditory evoked potential revealed left sensorineural hearing loss. He received ganciclovir treatment for 6 weeks, was discharged in good health, and continued conunder follow-up at the outpatient department. |
| Key Words:
CMV infection, Hearing loss, Newborn |
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