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Two Cases of Successful Treatment with Atropine Sulfate in Persistent Vomiting beyond Pyloromyotomy of Infantile Hypertrophic Pyrolic Stenosis

Journal of the Korean Pediatric Society 2000;43(5):704-709.
Published online May 15, 2000.
Two Cases of Successful Treatment with Atropine Sulfate in Persistent Vomiting beyond Pyloromyotomy of Infantile Hypertrophic Pyrolic Stenosis
Won Jung Kim, Min Jung Kim, Woo Jae Jo, Jae Young Kim, Sung Won Kim
Department of Pediatrics, St. Benedict Hospital, Pusan, Korea
유문절개술 후에도 지속적인 구토를 보인 유문협착증에서 Atropine Sulfate 투여로 호전된 2례
김원정, 김민정, 조우제, 김재영, 김성원
성분도병원 소아과
Abstract
Infantile hypertrophic pyloric stenosis(IHPS) is the most common condition requiring abdominal surgery in early infancy, and is caused by hypertrophied pyloric muscle. The development of successful surgical treatment in the early 1900s by Fredet and Ramstedt made it possible for infants worldwide to survive. Modern pediatric anesthetic techniques have virtually eliminated mortality from surgical management. Atropine sulfate is a cholinergic blocking agent with potent antimuscarinic activity that decreases peristaltic contractions by relaxing smooth muscles. We treated two cases of IHPS with incomplete pyloromyotomy in 3-month-old and 5-month-old male infants by administering atropine sulfate intravenously. They were free from vomiting after 5 days of intravenous atropine sulfate treatment. In these rare cases of persistent vomiting or refractory emesis following incomplete pyloromyotomy, there may be a role for atropine sulfate.
Key Words: Infantile hypertrophic pyloric stenosis, Pyloromyotomy, Atropine sulfate


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